MIT Technology Review released its highly anticipated annual Innovation issue in January 2026, identifying 10 breakthrough technologies that will reshape industries and solve critical global challenges. The list highlights major advances beyond AI, including transformative developments in biotech, energy storage, and climate technology.
Sodium-ion batteries emerged as a standout innovation, offering a cheaper and safer alternative to lithium-based systems. Built from abundant materials like salt, these batteries are backed by major manufacturers and public investment to power electrical grids and make electric vehicles more affordable worldwide. The technology addresses critical supply chain vulnerabilities while dramatically reducing costs for renewable energy storage.
In healthcare, personalized gene editing reached a major milestone when baby KJ became the first person to receive bespoke gene-editing treatment at just seven months old. Clinical trials are now planned, with personalized gene-editing therapies expected to gain regulatory approval within the next few years, potentially revolutionizing treatment for rare genetic disorders.